According to The Hollywood Reporter, Deadpool actor Ed Skrein (he played Francis/Ajax) has been cast as the cyborg villain Zapan in the Alita: Battle Angel movie. Apparently, in the film, Zapan will possess the powerful Damascus Blade, which in the manga actually belongs to Alita, so presumably she wrests it off him at some point in the story.
Set in the 26th century, Alita tells of a female cyborg (played by rosa Salazar) who is discovered in a scrapyard by a scientist. With no memory of her previous life except her deadly martial-arts training, the woman becomes a bounty hunter, tracking down criminals.
Robert Rodriguez (Sin City, From Dusk Till Dawn) is directing with James Cameron producing.