The CW have announced the villains of the piece will be an alien race called the Dominators, who do have their origins in the DC comics universe.
“This year, for our mega Arrowverse crossover, we’re taking inspiration from a DC crossover from the late 1980s known as ‘Invasion!’ which featured an alien race called the Dominators, who’d previously vexed the Legion of Super-Heroes,” reveals Arrow and DC’s Legends Of Tomorrow executive producer Marc Guggenheim. “We’re using cutting edge prosthetics and computer effects to achieve a feature film-quality look which is faithful to ‘Invasion!’ artist Todd McFarlane’s interpretation of the characters.”
The Dominators come to Earth after the emergence of metahumans suggests that humanity may evolve to be genetically superior to them… which they’re not happy about. Their solution? KILL THEM ALL!
In the comics, the Dominators are master geneticists who can manipulate the metagene to enhance members of their own caste. They actually first appeared in Adventure Comics #361 (1967) threatening the Legion of Super-Heroes in the 30th century, but were a major part of an alien alliance in Invasion! (1989).
The four-part CW superhero crossover will air in the States in December.